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Ashwagandha vs Rhodiola Rosea for Stress Relief: A Comprehensive Comparison

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Introduction
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Stress is an inevitable part of modern life, affecting millions of people worldwide. Adaptogenic herbs like ashwagandha and rhodiola rosea have gained popularity for their potential to mitigate stress and anxiety. While both herbs have been extensively studied, the question remains: which one is more effective for stress relief? In this article, we’ll delve into the comparison between ashwagandha and rhodiola rosea, exploring their unique benefits, potential interactions, and practical applications.

Quick Comparison Table
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SupplementActive CompoundRecommended DosagePotential Benefits
AshwagandhaWithanolides300-500 mg/dayReduces stress, anxiety, and cortisol levels; improves sleep quality (Lopresti et al., 2019)
Rhodiola RoseaRosavins100-200 mg/dayEnhances mental performance, reduces fatigue, and improves mood (Order et al., NA)

Detailed Comparison
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Both ashwagandha and rhodiola rosea have been traditionally used to promote relaxation, reduce stress, and improve overall well-being. However, their mechanisms of action and potential benefits differ.

Ashwagandha, an Indian herb, has been shown to reduce cortisol levels, anxiety, and stress in both animal and human studies (Lopresti et al., 2019; Bachour et al., 2025). The active compounds, withanolides, have been found to interact with the GABA receptor, promoting relaxation and reducing anxiety (Wal et al., 2019).

Rhodiola rosea, a golden flowering plant, has been traditionally used in Scandinavian countries to enhance mental performance and reduce fatigue. Its active compounds, rosavins, have been shown to increase the production of neurotransmitters like serotonin, dopamine, and norepinephrine, which play a crucial role in mood regulation (Order et al., NA).

In terms of effectiveness, ashwagandha has been found to be more effective in reducing cortisol levels and anxiety, while rhodiola rosea may be more beneficial for improving mental performance and reducing fatigue (Lopresti et al., 2019; Order et al., NA). However, it’s essential to note that individual results may vary, and the choice between ashwagandha and rhodiola rosea ultimately depends on personal preferences and needs.

Individual Product Breakdowns
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Ashwagandha
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Ashwagandha supplements are widely available in various forms, including capsules, tablets, and powders. When choosing an ashwagandha supplement, look for products that contain a standardized extract of withanolides, the active compounds responsible for its stress-relieving effects (Wal et al., 2019). Some popular ashwagandha supplements include:

  • Ashwagandha Extract by NOW Foods
  • Ashwagandha Root Powder by Organic India

Rhodiola Rosea
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Rhodiola rosea supplements are also widely available, often in combination with other adaptogenic herbs. When selecting a rhodiola rosea supplement, opt for products that contain a standardized extract of rosavins, the active compounds responsible for its mental performance-enhancing effects (Order et al., NA). Some popular rhodiola rosea supplements include:

  • Rhodiola Rosea Extract by Thorne Research
  • Rhodiola Rosea Root Powder by Gaia Herbs

Clear Verdict
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Choose ashwagandha if:

  • You’re looking for a natural supplement to reduce cortisol levels and anxiety
  • You prefer a herb with a more extensive body of research supporting its stress-relieving effects
  • You’re seeking a supplement that may help improve sleep quality

Choose rhodiola rosea if:

  • You’re looking for a natural supplement to enhance mental performance and reduce fatigue
  • You prefer a herb with a more rapid onset of action
  • You’re seeking a supplement that may help improve mood and reduce stress-related symptoms

Conclusion
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In conclusion, both ashwagandha and rhodiola rosea have been shown to be effective in reducing stress and anxiety, although their mechanisms of action and potential benefits differ. By understanding the unique characteristics of each herb, individuals can make informed decisions about which supplement may be best suited for their needs.

References
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A Wal, P Wal, AK Rai, et al. “Adaptogens with a special emphasis on Withania somnifera and Rhodiola rosea.” Nutrition and enhanced …, 2019. PubMed | Full Text PDF | DOI

A Ogorek, M Zasiadła, P Liszka, et al. “Potential interactions of popular adaptogens (Withania somnifera, Rhodiola rosea) with psychotropic drugs.” Quality in Sport, 2025. PubMed | Full Text PDF | DOI

AL Lopresti, SJ Smith, H Malvi, et al. “An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo …” Medicine, 2019. PubMed | Full Text PDF | DOI

TY Order, USD Australia, EUR Finland, et al. “Rhodiola Rosea and Stress Resilience: A Natural Cortisol Regulator.” NA, NA. PubMed | Full Text PDF | DOI

G Bachour, A Samir, S Haddad, et al. “Effects of Ashwagandha Supplements on Cortisol, Stress, and Anxiety Levels in Adults: A Systematic Review and Meta-Analysis.” BJPsych Open, 2025. PubMed | Full Text PDF | DOI

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